We develop noninvasive medical ultrasound technologies for diagnostics, monitoring, and therapy for clinically relevant problems. Our research is highly multidisciplinary, combining engineering, physics, biology, chemistry and medicine. We utilize the unique ability of sound waves to penetrate deep into the body, in some cases even through an intact skull, and couple it with gas-bubbles. These bubbles are efficient theranostic probes that can be used for simultaneous imaging and controlled therapy at a targeted site. We develop enhanced ultrasound-mediated gene delivery methods, noninvasive ultrasound surgery, and safe and precise blood brain barrier opening for brain therapy. In parallel, we are developing optically-inspired ultrasonic techniques for overcoming current limitations in ultrasound imaging. Current interests include 3D ultrasound, super-resolution, image processing and machine learning.
פרופ' טלי אילוביץ
ראש מרכז במנהלת הפקולטה להנדסה
Research Interests
Curriculum Vitae
2024- Associate Professor
School of Biomedical Engineering, Tel Aviv University, Israel
2019-2024 Senior Lecturer (Assistant Professor aquivalent)
Department of Biomedical Engineering, Tel Aviv University, Israel
2018-2019 Postdoctoral Fellow, Stanford University, USA
Department of Radiology, School of Medicine, Stanford University, Stanford, California, USA
2016-2018 Postdoctoral Fellow, University of California at Davis, USA
Department of Biomedical Engineering, Faculty of Engineering, University of California at Davis, Davis, California, USA
2012-2016 Ph.D. Electrical Engineering
Department of Electrical Engineering, Faculty of Engineering, Bar Ilan University, Israel.
2010-2012 M.Sc. Electrical Engineering
Department of Electrical Engineering, Faculty of Engineering, Bar Ilan University, Israel.
2007-2011 B.Sc. Electrical Engineering
Department of Electrical Engineering, Faculty of Engineering, Bar Ilan University, Israel.
תחומי מחקר
פיתוח טכנולוגיות חדשות בתחום האולטרסאונד הרפואי. הדמיית אולטרסאונד בתלת מימד, סופר-רזולוציה, עיצוב חזית הגל, עיבוד תמונה, ולמידת מכונה. אולטרסאונד טיפולי בשילוב עם בועות לצורך העברת תרופות, ריפוי גני, פתיחת מחסום הדם-מוח, אבלציות מכניות לטיפול בסרטן.
Selected publications
M. Shumer-Elbaz, N. Ad-El, Y. Chulanova, D. Brier, M. Goldsmith, M. Bismuth, A. Brosque, R. Gattegno, D. Sher, A. Gutkin, D. Bar-On, D. Friedmann-Morvinski, D. Peer, and T. Ilovitsh, Low-frequency ultrasound-mediated blood-brain barrier opening enables noninvasive lipid nanoparticle RNA delivery to glioblastoma. The Journal of Controlled Release (2025).
B. Glickstein, M. Bismuth, R. Gattegno, R. Aronovich, Y. Feng, and T. Ilovitsh, Volumetric nanodroplets-enhanced ultrasound surgery combined with immune checkpoint inhibition as a cancer therapy platform. Small (2024).
R. Gattegno, L. Arbel, N. Riess, S. Katz, and T. Ilovitsh, Enhanced capillary delivery with nanobubble-mediated blood-brain barrier opening and advanced high resolution vascular segmentation. The Journal of Controlled Release (2024)
K.T. Karlinsky, M. Bismuth, R. Aronovich, T. Ilovitsh, Nonlinear Frequency Mixing Ultrasound Imaging of Nanoscale Contrast Agents. IEEE Transactions on Biomedical Engineering (2023).
M. Bismuth, S. Katz, T. Mano, R. Aronovich, D. Hershkovitz, A. A. Exner, and T. Ilovitsh, Low frequency nanobubble-enhanced ultrasound mechanotherapy for noninvasive cancer surgery. Nanoscale 14, 13614-13627 (2022).
T. Ilovitsh, et al. "Low-frequency ultrasound-mediated cytokine transfection enhances T cell recruitment at local and distant tumor sites." Proceedings of the National Academy of Sciences (2020).
