ד"ר דקל רוזנפלד

I received my B.Sc. (Cum Lauda, 2007), M.Sc. in a direct track (2010) and Ph.D. (2015) in Biomedical Engineering from the Technion, Israel Institute of Technology.  My Ph.D. research focused on understating the involvement of mechanical forces in engineered tissues focusing on vascularized engineered tissues and differentiation of embryonic stem cells. On 2016 I started my postdoctoral research in the Massachusetts Institute of Technology in the Bioelectronics group, where I developed the magnetothermal approach for peripheral organs and nerve regeneration. I later worked as Research Scientist in the Research Laboratory of Electronics in MIT where I studied the gut-brain axis. Since 2022 I am a Senior Lecturer in the department of Biomedical Engineering at Tel Aviv University.

We develop magnetic functional materials to interact with electrogenic cells for neuromodulation and control over peripheral organ function. These tools allow remote control on calcium-dependent processes via activation of ion channels such as heat sensitive ion channels. It provides spatial and temporal resolution in a minimally invasive procedure demonstrated both in vitro and in vivo. We developed a novel approach to control the release of adrenal stress hormones to treat hormonal imbalance in mental health disorders such as post trauma stress disorder.

Our ultimate goals are developing new tools that advance the biomedical research to repair organ dysfunction and studying the organ-brain communication in health and disease.

1. Dena Shahriari*, Dekel Rosenfeld*, Polina Anikeeva. Emerging frontier of peripheral nerve and organ interfaces. Neuron. In press *Equal contribution
2. Dekel Rosenfeld, Alexander W. Senko, Junsang Moon, Isabel Yick, Georgios Varnavides, Danijela Gregureć, Florian Koehler, Po-Han Chiang, Michael G. Christiansen, Lisa Y. Maeng, Alik S. Widge and Polina Anikeeva. 2020. Transgene-free remote magnetothermal regulation of adrenal hormones. Science Advances. 6 (15), eaaz3734.
3. Dekel Rosenfeld, Shira Landau, Yulia Shandalov, Noa Raindel, Erez Shor, Yaron Blinder, Herman Vandenburgh, David Mooney and Shulamit Levenberg. 2016. Morphogenesis of 3D vascular network is .regulated by tensile forces. Proc Natl Acad Sci U S A. 113(12): 3215–322.