ד"ר אנה תובר

Dr. Ana Tobar, MD

Director of the Nephropathology Unit

Rabin Medical Center

Department of Pathology

Beilinson Hospital

Education

1981-1986             Faculty of Medicine, Buenos Aires University, Argentina

1986                      MD degree

1987-1989             Resident, Department of Pediatrics, Children’s General Hospital, Ricardo Gutierrez, Buenos Aires, Argentina.

1991-1997             Resident, Department of Pathology, Beilinson Medical Center, Petah Tiqwa, Israel.

1997                      Specialized in Pathology

                             License No. 16015

1991-current       Tutor and lecturer to medical students in specific and general pathology,

                             Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

1997-current       Senior Resident, Department of Pathology

2005-2006            Clinical Fellowship in Nephropathology and Renal Transplantation, Department of Laboratory Medicine and Pathobiology, Faculty  of Medicine, University of Toronto

Research areas

-PAX 8 EXPRESSION IN WILMS TUMORS AND ITS IMPLICATIONS

- ANDROGEN AND ESTROGEN RECEPTOR EXPRESSION IN HEPATOCELLULAR CARCINOMA

Lists of publications (2008-2013)

1. N. Rosenfeld, R. Aharonov, E. Meiri, S. Rosenwald, Y. Spector, M. Zepeniuk, H. Benjamin, N. Shabes, S. Tabak, A. Levy, D. Lebanony, Y. Goren,

          E. Silberschein, N. Targan, A. Ben-Ari, S. Gilad, N. Sion-Vardy, A.Tobar,

          M. Feinmesser, O. Kharenko, O. Nativ, D. Nass, M. Perelman,

          A. Yosepovich, B. Shalmon, S. Polak-Charcon, E. Fridman, A. Avniel,

          I. Bentwich, Z. Bentwich, D. Cohen, A. Chajut, I. Barshack.

          MicroRNA accurately identify cancer tissue origin.

          Nat Biotechnol 26: 462-469, 2008. Epub 2008 Mar 23.

2. D. Nass, S. Rosenwald, E. Meiri, S. Gilad, H. Tabibian-Keissar,

          A. Schlosberg, H. Kuker, N. Sion-Vardy, A. Tobar, O. Kharenko, E. Sitbon,

          G. Lithwick, E. Elyakim, H. Cholakh, H. Gibori, Y. Spector, Z. Bentwich,

          I. Barshack, N. Rosenfeld.

          MiR-92b and miR-9/9 are specifically expressed in brain primary tumors and can be used to differentiate primary from metastatic brain tumors.

          Brain Pathol Jul; 19  (3): 375-83. Epub 2008 Jul 2

3. B. Medalion, A. Tobar, Z. Yosibash, A. Stamler, E. Sharoni, E. Snir, E. Porat, E. Hochhauser.

          Vasoreactivity and histology of the radial artery: comparison of open versus endoscopic approaches.

          Europ J Cardiothoracic Surg 34: 845-849, 2008,

4. Y. Ori, M. Herman, A. Tobar, G. Chernin, U. Gafter, A. Chagnac, O.B. Izhak, A. Korzets.

          Acute phosphate nephropathy-an emerging threat.

          Am J Med Sci 336: 309-314, 2008.

5.  Hecht G, Eventov-Friedman S, Rosen C, Shezen e, Tchorsh D, Aronovich a, Freud E, Golan H, El-Hasid R, Katchman H, Hering BJ, Zung A, Kra-Oz Z, Shaked-Mishan P, Yusim A, Shtabsky A, Idelevitch P, Tobar A, Harmelin A, Bachar-Lustig E, Reisner Y.

          Embryonic pig pancreatic tissue for the treatment of diabetes in a non human primate model.

          Proc Natl Acad Sci USA, May, 106 (21): 8659-64, 2009

6.  Freidkin I, Herman M, Tobar A, Chagnac A, Ori Y, Korzets A, Gafter U.

          Effects of histone deacetylase inhibitors on rat mesangial cells.

          Am J Physiol Renal Physiol Feb; 298 (2): F426-34. 2010

7. Rosenwald S, Giald S, Benjamin S, Lebanony D, Dromi N, Faerman A, Benjamin H, Tamir R, Ezagouri M, Gore E, Barshack I, Nass D, Tobar A, Feinmesser M, Rosenfeld N, Leizerman I, Asjkenazi K, Spector Y, Chajut A, Aharonov R

          Validation of a micro RNA based qRT-PCR test for accurate identification of tumor tissue origin

          Mol Pathol Jun; 23(6): 814-23, 2010

8.  Feinmesser M, Veltman V, Morgenstern S, Tobar A, Gutman H, Kaganovsky    E, Tzabari C, Sulkes J, Okon E

          Different patterns of expression of the erbB family of receptor tyrosine kinases in common nevi, dysplastic nevi, and primary malignant melanoma: an immunohistochemical study

          Am J Dermatopahtol. Oct; 32(7):665-75, 2010

9. John R, Konvalinka A, Tobar A, Kim SJ, Reich HN, Herzenberg AM

           Determinants of long term graft outcome in transplant glomerulopathy

           Transplantation, Oct 15; 90(7):757-64, 2010

10. Cohen R, Shainberg A, Hochhauser E, Cheporko Y, Tobar A, Birk E, PInhas L,            

           Leipziger J, Don J and Porat E.

          UTP reduces infarct size and improves mice heart function after myocardial

          Infarct via P2Y2 receptor, Biochem Pharmacol. Nov 1; 82 (9): 1126-33 Epub 2011 Aug 3

11. Aviner S, Ronen M, London D, Tobar A, Zangen S.

          Langhernas cell histiocytosis in a premature baby presenting with skin-           isolated disease: case report and literature review

          Acta Paediatr. Dec; 97 (12): 1751-4. Epub 2008 Aug 27 Review

12.  Hemda Schmilovitz-Weiss, Ana Tobar, Marisa Halpern, Izhar Levy, Esther Shabtai and Ziv Ben Ari

          Tissue expression of squamous cellular carcinoma antigen and KI67 in hepatocellular carcinoma- correlation with prognosis: A historical prospective study

          Diagnostic pathology 2011, 6: 121