Numerous cysts appear in this liver from a patient with autosomal dominant polycystic kidney disease (ADPKD). Such cases occur in adults and manifest with renal failure beginning in middle age. Sometimes the liver (as seen here) can be affected as well by polycystic change. Less commonly the pancreas is involved. These patients with ADPKD can also have berry aneurysms involving the cerebral arteries in the circle of Willis.

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